9 zips
| Zip Code | City | Population ↓ |
|---|---|---|
| 78861 | Hondo | 14,008 |
| 78016 | Devine | 11,670 |
| 78009 | Castroville | 9,151 |
| 78059 | Natalia | 7,061 |
| 78056 | Mico | 2,526 |
| 78039 | La Coste | 1,862 |
| 78850 | D Hanis | 779 |
| 78886 | Yancey | 286 |
| 78066 | Rio Medina | 259 |
The data shown reflect ZCTAs from the US Census. As of 2024, there are 9 ZCTAs in Medina County, Texas (US Census).