7 zips
| Zip Code | City | Population ↓ |
|---|---|---|
| 78119 | Kenedy | 7,270 |
| 78118 | Karnes City | 4,676 |
| 78151 | Runge | 1,378 |
| 78117 | Hobson | 661 |
| 78116 | Gillett | 226 |
| 78144 | Panna Maria | 47 |
| 78111 | Ecleto | 0 |
The data shown reflect ZCTAs from the US Census. As of 2024, there are 7 ZCTAs in Karnes County, Texas (US Census).