St. Lawrence is a town located in Hand County, South Dakota. St. Lawrence has a 2026 population of 161. St. Lawrence is currently declining at a rate of -1.23% annually and its population has decreased by -2.42% since the most recent census, which recorded a population of 165 in 2020.
The median household income in St. Lawrence is $46,000 with a poverty rate of 8.72%. The median age in St. Lawrence is 49.6 years: 49.5 years for males, and 51.2 years for females. For every 100 females there are 135.6 males.