Johnsonville
- County:
- Florence County
- County Seat:
- No
- Area (mi²):
- 2.116
- State:
- South Carolina
Johnsonville is a city located in Florence County, South Carolina. Johnsonville has a 2026 population of 1,350. Johnsonville is currently growing at a rate of 0.22% annually but its population has decreased by -0.44% since the most recent census, which recorded a population of 1,356 in 2020.
The median household income in Johnsonville is $44,830 with a poverty rate of 20.94%. The median age in Johnsonville is 36 years: 38.2 years for males, and 35.9 years for females. For every 100 females there are 87.0 males.