Scio is a village located in Harrison County, Ohio. Scio has a 2026 population of 646. Scio is currently declining at a rate of -1.22% annually and its population has decreased by -3.58% since the most recent census, which recorded a population of 670 in 2020.
The median household income in Scio is $41,667 with a poverty rate of 36.48%. The median age in Scio is 30.6 years: 29.6 years for males, and 35.7 years for females. For every 100 females there are 107.4 males.