Prairie Home is a city located in Cooper County, Missouri. Prairie Home has a 2026 population of 266. Prairie Home is currently growing at a rate of 1.14% annually and its population has increased by 1.53% since the most recent census, which recorded a population of 262 in 2020.
The median household income in Prairie Home is $53,750 with a poverty rate of 8.76%. The median age in Prairie Home is 48.3 years: 44.8 years for males, and 53.5 years for females. For every 100 females there are 88.7 males.