Old Appleton
- County:
- Cape Girardeau County
- County Seat:
- No
- Area (mi²):
- 0.121
- State:
- Missouri
Old Appleton is a town located in Cape Girardeau County, Missouri. Old Appleton has a 2026 population of 75. Old Appleton is currently growing at a rate of 1.35% annually and its population has increased by 1.35% since the most recent census, which recorded a population of 74 in 2020.
The median household income in Old Appleton is $54,306 with a poverty rate of 4.59%. The median age in Old Appleton is 37.1 years: 37.3 years for males, and 30.8 years for females. For every 100 females there are 153.5 males.