New Melle
- County:
- St. Charles County
- County Seat:
- No
- Area (mi²):
- 1.789
- State:
- Missouri
New Melle is a city located in St. Charles County, Missouri. New Melle has a 2026 population of 547. New Melle is currently growing at a rate of 0.37% annually but its population has decreased by -0.36% since the most recent census, which recorded a population of 549 in 2020.
The median household income in New Melle is $114,375 with a poverty rate of 4.42%. The median age in New Melle is 51.9 years: 51.7 years for males, and 52 years for females. For every 100 females there are 73.8 males.