New Madrid
- County:
- New Madrid County
- County Seat:
- Yes
- Area (mi²):
- 4.501
- State:
- Missouri
New Madrid is a city located in New Madrid County, Missouri. New Madrid has a 2026 population of 2,597. It is also the county seat of New Madrid County. New Madrid is currently declining at a rate of -0.73% annually and its population has decreased by -6.14% since the most recent census, which recorded a population of 2,767 in 2020.
The median household income in New Madrid is $57,727 with a poverty rate of 12.32%. The median age in New Madrid is 38.9 years: 38.2 years for males, and 40.9 years for females. For every 100 females there are 136.8 males.