Keytesville
- County:
- Chariton County
- County Seat:
- Yes
- Area (mi²):
- 0.769
- State:
- Missouri
Keytesville is a city located in Chariton County, Missouri. Keytesville has a 2026 population of 447. It is also the county seat of Chariton County. Keytesville is currently declining at a rate of 0% annually and its population has increased by 0.22% since the most recent census, which recorded a population of 446 in 2020.
The median household income in Keytesville is $40,682 with a poverty rate of 12.59%. The median age in Keytesville is 49.7 years: 48 years for males, and 50.2 years for females. For every 100 females there are 104.2 males.