Jacksonville is a village located in Randolph County, Missouri. Jacksonville has a 2026 population of 121. Jacksonville is currently declining at a rate of -0.82% annually and its population has decreased by -1.63% since the most recent census, which recorded a population of 123 in 2020.
The median household income in Jacksonville is $42,813 with a poverty rate of 14.29%. The median age in Jacksonville is 38.3 years: 27.8 years for males, and 57 years for females. For every 100 females there are 107.4 males.