East Prairie
- County:
- Mississippi County
- County Seat:
- No
- Area (mi²):
- 1.25
- State:
- Missouri
East Prairie is a city located in Mississippi County, Missouri. East Prairie has a 2026 population of 2,859. East Prairie is currently declining at a rate of -0.66% annually and its population has decreased by -2.69% since the most recent census, which recorded a population of 2,938 in 2020.
The median household income in East Prairie is $34,637 with a poverty rate of 21.18%. The median age in East Prairie is 39.7 years: 26.8 years for males, and 42.7 years for females. For every 100 females there are 96.2 males.