Centerville is a city located in Reynolds County, Missouri. Centerville has a 2026 population of 163. It is also the county seat of Reynolds County. Centerville is currently declining at a rate of -0.61% annually and its population has decreased by -2.4% since the most recent census, which recorded a population of 167 in 2020.
The median household income in Centerville is $37,321 with a poverty rate of 19.38%. The median age in Centerville is 35.9 years: 32.5 years for males, and 38.8 years for females. For every 100 females there are 151.5 males.