Waynesboro
- County:
- Wayne County
- County Seat:
- Yes
- Area (mi²):
- 12.693
- State:
- Mississippi
Waynesboro is a city located in Wayne County, Mississippi. Waynesboro has a 2026 population of 4,507. It is also the county seat of Wayne County. Waynesboro is currently declining at a rate of -0.16% annually and its population has decreased by -1.36% since the most recent census, which recorded a population of 4,569 in 2020.
The median household income in Waynesboro is $31,684 with a poverty rate of 28.17%. The median age in Waynesboro is 39.1 years: 32.3 years for males, and 40.4 years for females. For every 100 females there are 99.2 males.