Isola
- County:
- Humphreys County
- County Seat:
- No
- Area (mi²):
- 0.739
- State:
- Mississippi
Isola is a town located in Humphreys County, Mississippi. Isola has a 2026 population of 583. Isola is currently declining at a rate of -1.52% annually and its population has decreased by -8.04% since the most recent census, which recorded a population of 634 in 2020.
The median household income in Isola is $37,981 with a poverty rate of 35.31%. The median age in Isola is 34.9 years: 36.1 years for males, and 33.8 years for females. For every 100 females there are 62.1 males.